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VEGFA / VEGF
vascular endothelial growth factor A
VEGFA / VEGF is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
| Gene Name: | vascular endothelial growth factor A |
| Family/Subfamily: | PDGF , not assigned-PDGF |
| Synonyms: | VEGFA, VPF, Vascular permeability factor, VEGF, VEGF-A, MVCD1 |
| Target Sequences: | NM_003376 NP_003367.4 P15692 |
Publications (22)
1
Vascular endothelial growth factor, wild-type p53, and angiogenesis in early operable non-small cell lung cancer. Giatromanolaki A, Koukourakis MI, Kakolyris S, Turley H, O'Byrne K, Scott PA, Pezzella F, Georgoulias V, Harris AL, Gatter KC. Clinical cancer research : an official journal of the American Association for Cancer Research. 1998 4:3017-24.
[PubMed:9865915]
2
Expression of VEGF in routinely fixed material using a new monoclonal antibody VG1. Turley H, Scott PA, Watts VM, Bicknell R, Harris AL, Gatter KC. The Journal of pathology. 1998 186:313-8.
[PubMed:10211122]
3
Assessment of vascular maturation in non-small cell lung cancer using a novel basement membrane component, LH39: correlation with p53 and angiogenic factor expression. Kakolyris S, Giatromanolaki A, Koukourakis M, Leigh IM, Georgoulias V, Kanavaros P, Sivridis E, Gatter KC, Harris AL. Cancer research. 1999 59:5602-7.
[PubMed:10554041]
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VEGFA / VEGF Rabbit anti-Rat Polyclonal Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
VEGFA / VEGF Mouse anti-Human Monoclonal (VG76e) Antibody
Sheep, Bovine, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
Cancer Pathology
Cancer
VEGFA / VEGF Goat anti-Human Polyclonal (aa250-300) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µg/$485
Cancer Pathology
Cancer
VEGFA / VEGF Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
VEGFA / VEGF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, Neut, WB
Unconjugated
50 µg/$460
VEGFA / VEGF Rabbit anti-Human Polyclonal (aa59-74) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
VEGFA / VEGF Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$564
VEGFA / VEGF Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
VEGFA / VEGF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$396
VEGFA / VEGF Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$326
VEGFA / VEGF Goat anti-Human Polyclonal Antibody
Human
ELISA, IHC-P, WB
Unconjugated
0.1 mg/$579
VEGFA / VEGF Mouse anti-Human Monoclonal (VEGF/1063) Antibody
Human
IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
VEGFA / VEGF Mouse anti-Human Monoclonal (VG1) Antibody
Mouse, Dog, Rat, Human
IF, IHC-P, WB
Unconjugated
0.1 mg/$386
VEGFA / VEGF Rabbit anti-Human Polyclonal (aa66-95) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
VEGFA / VEGF Goat anti-Human Polyclonal Antibody
Mouse, Dog, Rat, Human, Monkey
IF, WB
Unconjugated
600 µg/$409
Sandwich
96-Well Strip Plate
Pig
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$779
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$634
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$568
E. coli
His, N-Terminal
25.1kDa
10 µg/$295; 50 µg/$532; 200 µg/$1,049; 100 µg/$850; 1 mg/$2,215; 500 µg/$1,733; 5 mg/$3,711; 2 mg/$2,407
Yeast
His
51.7 kD
1 mg/$1,973; 100 µg/$679; 20 µg/$429
Sandwich
96-Well Strip Plate
Rabbit
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$582
E. coli
His
20.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
VEGFA / VEGF Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
VEGFA / VEGF Rabbit anti-Human Polyclonal (HRP) Antibody
Human
IHC, WB
HRP Conjugated
100 µg/$552
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