VAV3

vav 3 guanine nucleotide exchange factor

Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2 (ITGB2)-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3 (ITGB3)-mediated adhesion. Does not affect integrin beta-1 (ITGB1)-mediated adhesion.

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Products

Antibodies (36)

Proteins (8)

ELISA Kits (5)

Type

Cell-Based (1)

Over-Expression Lysate (4)

Primary (36)

Recombinant (4)

Sandwich (4)

Target

VAV3 (49)

Reactivity

Human (39)

Mouse (15)

Rat (1)

Monkey (2)

Application

IHC (6)

IHC-P (2)

WB (33)

ELISA (9)

ICC (1)

IP (2)

Peptide-ELISA (3)

Host

rabbit (35)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (14)

Clonality

polyclonal pc (36)

Format

96-Well Microplate (1)

96-Well Strip Plate (4)

APC (2)

APC Conjugated (2)

Biotin Conjugated (3)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (19)

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Epitope

aa183-380 (8)

aa398-583 (8)

pTyr173 (3)

110-190 aa (2)

Internal (1)

aa118-167 (1)

aa200-250 (1)

aa566-591 (1)

aa567-578 (1)

aa768-802 (1)

p173 (1)

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Publications

No (49)

Sample Type

Adherent Cell Cultures (1)

Plasma (4)

Serum (4)

Tissue Homogenates (2)

Tag

His (2)

Myc-DDK (Flag) (6)

Species

Human (6)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (4)

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IHC-plus™ VAV3 Antibody (aa567-578) LS-B3237

(4.0) Rating

Antibody:

VAV3 Goat anti-Human Polyclonal (aa567-578) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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VAV3 Antibody (aa566-591) LS-C11019

Antibody:

VAV3 Rabbit anti-Human Polyclonal (aa566-591) Antibody

Reactivity:

Human, Monkey

Applications:

ICC, IHC, IP, WB

Format:

Unconjugated

Price:

200 µg/$725

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Human VAV3 (Sandwich ELISA) ELISA Kit - LS-F14030

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human VAV3 Protein (Recombinant His) (aa183-380) - LS-G15587

Source:

E. coli

Tag:

His

Molecular Weight:

24.7 kDa

Price:

10 µg/$339; 50 µg/$802; 100 µg/$1,214; 200 µg/$1,430; 1 mg/$2,728; 500 µg/$2,223; 5 mg/$5,601; 2 mg/$2,988

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VAV3 Antibody LS-C502148

Antibody:

VAV3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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VAV3 Antibody (HRP) LS-C502155

Antibody:

VAV3 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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VAV3 Antibody (Biotin) LS-C502153

Antibody:

VAV3 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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VAV3 Antibody (FITC) LS-C502150

Antibody:

VAV3 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IHC-plus™ VAV3 Antibody (aa200-250) LS-B15490

(4.0) Rating

Antibody:

VAV3 Rabbit anti-Human Polyclonal (aa200-250) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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VAV3 Antibody (aa183-380) LS-C296976

Antibody:

VAV3 Rabbit anti-Human Polyclonal (aa183-380) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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VAV3 Antibody (110-190 aa) LS-C381427

Antibody:

VAV3 Rabbit anti-Human Polyclonal (110-190 aa) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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VAV3 Antibody (p173) LS-C825691

Antibody:

VAV3 Rabbit anti-Human Polyclonal (p173) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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VAV3 Antibody LS-C742590

Antibody:

VAV3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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VAV3 Antibody (110-190 aa) LS-C386627

Antibody:

VAV3 Rabbit anti-Human Polyclonal (110-190 aa) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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VAV3 Antibody (phospho-Tyr173) LS-C825692

Antibody:

VAV3 Rabbit anti-Human Polyclonal (pTyr173) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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VAV3 Antibody (aa118-167) LS-C200813

Antibody:

VAV3 Rabbit anti-Human Polyclonal (aa118-167) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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VAV3 Antibody (aa768-802) LS-C392760

Antibody:

VAV3 Rabbit anti-Human Polyclonal (aa768-802) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

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VAV3 Antibody (phospho-Tyr173) LS-C11020

Antibody:

VAV3 Rabbit anti-Human Polyclonal (pTyr173) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

10 Blots/$842

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VAV3 Antibody LS-C40173

Antibody:

VAV3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$688

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VAV3 Antibody LS-C771709

Antibody:

VAV3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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VAV3 Antibody (aa398-583) LS-C296978

Antibody:

VAV3 Rabbit anti-Human Polyclonal (aa398-583) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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VAV3 Antibody (aa398-583, Biotin) LS-C299876

Antibody:

VAV3 Rabbit anti-Human Polyclonal (aa398-583) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

VAV3 Antibody (phospho-Tyr173) LS-C415794

Antibody:

VAV3 Rabbit anti-Human Polyclonal (pTyr173) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

VAV3 Antibody (Internal) LS-C368555

Antibody:

VAV3 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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VAV3 Antibody LS-C750357

Antibody:

VAV3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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