USP19

ubiquitin specific peptidase 19

Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.

☰ Filters

Products

Proteins (2)

Type

Over-Expression Lysate (2)

Target

USP19 (2)

Publications

No (2)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

Select

Human USP19 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86777

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

145.5 kDa

Price:

20 µg/$215

Select

USP19 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115144

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

145.5 kDa

Price:

100 µg/$710

Viewing 1-2 of 2 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.