Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
Gene Name: | uroporphyrinogen III synthase |
Synonyms: | UROS, Hydroxymethylbilane hydrolyase, UROIIIS, Uroporphyrinogen-III synthase, Uroporphyrinogen III synthase |
Target Sequences: | NM_000375 NP_000366.1 P10746 |
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