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6737 Mowry Ave
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UMOD / Uromodulin
uromodulin
UMOD / Uromodulin is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.
| Gene Name: | uromodulin |
| Synonyms: | UMOD, ADMCKD2, FJHN, HNFJ, MCKD2, THGP, THP, Uromucoid, Tamm-Horsfall glycoprotein, HNFJ1, Uromodulin |
| Target Sequences: | NM_003361 NP_003352.2 P07911 |
Publications (6)
1
Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. Jayachandran M, Lugo G, Heiling H, Miller VM, Rule AD, Lieske JC. Biology of sex differences. 2015 6:2. (Flo; Human)
[Full Text Article]
[PubMed:25729563]
[PMC:PMC4345020]
Related Antibodies: LS-B3105.
2
Specific renal parenchymal-derived urinary extracellular vesicles identify age-associated structural changes in living donor kidneys. Turco AE, Lam W, Rule AD, Denic A, Lieske JC, Miller VM, Larson JJ, Kremers WK, Jayachandran M. Journal of Extracellular Vesicles. 2016 5:29642. (Flo; Human)
[PubMed:26837814]
[PMC:PMC4737715]
Related Antibodies: LS-B3105.
3
Novel fixed z-direction (FiZD) kidney primordia and an organoid culture system for time-lapse confocal imaging. Saarela U, Akram SU, Desgrange A, Rak-Raszewska A, Shan J, Cereghini S, Ronkainen VP, Heikkilä J, Skovorodkin I, Vainio SJ. Development (Cambridge, England). 2017 144:1113-1117. (IHC; Mouse)
[Full Text Article]
[PubMed:28219945]
[PMC:PMC5358112]
☰ Filters
Products
Antibodies
(63)
Type
Primary
(63)
Target
UMOD / Uromodulin
(63)
Reactivity
Human
(38)
Mouse
(12)
Rat
(10)
Bovine
(3)
Chimpanzee
(6)
Dog
(13)
Gibbon
(3)
Guinea pig
(3)
Horse
(3)
Monkey
(1)
Orangutan
(3)
Pig
(8)
Application
IHC
(16)
IHC-Fr
(4)
IHC-P
(8)
WB
(58)
ELISA
(8)
IF
(4)
IP
(1)
Peptide-ELISA
(4)
Host
rabbit
(56)
mouse
(4)
goat
(2)
sheep
(1)
Product Group
IHCPlus
(2)
PathPlus Cancer
(4)
Isotype
IgG
(17)
IgG2b
(4)
Clonality
monoclonal mc
(4)
polyclonal pc
(59)
Clone
10.32
(4)
Format
APC
(4)
APC Conjugated
(5)
Azide-free
(1)
Biotin Conjugated
(7)
Cy3 Conjugated
(4)
Cy7 Conjugated
(4)
FITC Conjugated
(8)
HRP Conjugated
(8)
PE Conjugated
(5)
Unconjugated
(22)
Epitope
aa30-150
(8)
aa32-151
(8)
aa334-589
(8)
aa335-590
(8)
aa352-380
(7)
C-Terminus
(4)
aa503-552
(4)
Internal
(2)
Val378
(1)
aa24-618
(1)
aa329-378
(1)
aa525-536
(1)
aa603-614
(1)
Publications
No
(62)
Yes
(1)
UMOD / Uromodulin Mouse anti-Human Monoclonal (FITC) (10.32) Antibody
Dog, Human
ELISA, IF, IHC, IHC-Fr, IHC-P
FITC Conjugated
50 µg/$460
Cancer
UMOD / Uromodulin Mouse anti-Human Monoclonal (10.32) Antibody
Dog, Human
IF, IHC, IHC-Fr, IHC-P
Unconjugated
50 µg/$460
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa352-380) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
UMOD / Uromodulin Mouse anti-Human Monoclonal (10.32) Antibody
Human
IF, IHC, IHC-Fr, IHC-P
Unconjugated
1 ml/$503
UMOD / Uromodulin Rabbit anti-Rat Polyclonal (aa30-150) Antibody
Rat
WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa503-552) Antibody
Human
WB
Unconjugated
100 µl/$424
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa503-552) (Biotin) Antibody
Dog, Guinea pig, Bovine, Horse, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
Cancer
UMOD / Uromodulin Rabbit anti-Human Polyclonal (Val378) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
UMOD / Uromodulin Mouse anti-Human Monoclonal (HRP) (10.32) Antibody
Human
IF, IHC, IHC-Fr, IHC-P
HRP Conjugated
100 µg/$466
UMOD / Uromodulin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
UMOD / Uromodulin Sheep anti-Mouse Polyclonal (aa24-618) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$930
UMOD / Uromodulin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Cancer
UMOD / Uromodulin Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC-P, WB
Unconjugated
50 µl/$460
UMOD / Uromodulin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
Cancer
UMOD / Uromodulin Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
60 µl/$460
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa352-380) Antibody
Human
IHC, WB
Unconjugated
200 µl/$734
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa352-380) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa352-380) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa352-380) (Azide-free) (HRP) Antibody
Human
IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa352-380) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa352-380) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
UMOD / Uromodulin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
UMOD / Uromodulin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
UMOD / Uromodulin Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
UMOD / Uromodulin Rabbit anti-Human Polyclonal (aa329-378) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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product results
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