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Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Gene Name: | UDP-glucose glycoprotein glucosyltransferase 2 |
Synonyms: | UGGT2, HUGT2, UGT2, UGCGL2 |
Target Sequences: | NM_020121 NP_064506.3 Q9NYU1 |
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