Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
UGDH / UDPGDH converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
Gene Name: | UDP-glucose 6-dehydrogenase |
Synonyms: | UGDH, UDP-GlcDH, UDPGDH, UDP-Glc dehydrogenase, UGD, UDP-glucose 6-dehydrogenase, GDH, UDP-glucose dehydrogenase |
Target Sequences: | NM_003359 NP_003350.1 O60701 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.