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UCN3 / SPC
urocortin 3
UCN3 / SPC is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.
| Gene Name: | urocortin 3 |
| Synonyms: | UCN3, SPC, Stresscopin, Urocortin 3 (stresscopin), Urocortin 3, Urocortin III, Urocortin-3, UCNIII, SCP, Ucn III |
| Target Sequences: | Q969E3 Q969E3 |
Publications (3)
1
Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise. Kavalakatt S, Khadir A, Madhu D, Hammad M, Devarajan S, Abubaker J, Al-Mulla F, Tuomilehto J, Tiss A. Frontiers in endocrinology. 2019 November;10: [Full Text Article]
[PubMed:31781037]
[PMC:PMC6851015]
2
Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes. Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Heikki A Koistinen , Fahd Al-Mulla, Jaakko Tuomilehto , Jehad Abubaker, Ali Tiss. Scientific reports. 2021 Aug;11:15666. [Full Text Article]
[PubMed:34341463]
[PMC:PMC8329193]
3
Circulating levels of urocortin neuropeptides are impaired in children with overweight. Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Sriraman Devarajan, Samia Warsame, Hessa AlKandari, Maria AlMahdi, Heikki A Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Jehad Abubaker, Ali Tiss. Obesity (Silver Spring, Md.). 2022 Feburary;30:472-481. [Full Text Article]
[PubMed:35088550]
[PMC:PMC9305428]
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Products
ELISA Kits
(11)
Type
Custom
(2)
Sandwich
(8)
Sandwich CLIA
(1)
Target
UCN3 / SPC
(11)
Reactivity
Human
(4)
Mouse
(1)
Chicken
(1)
Guinea pig
(1)
Monkey
(1)
Rabbit
(1)
Sheep
(1)
Format
12 x 8-Well Microstrips
(2)
96-Well Strip Plate
(9)
Publications
No
(10)
Yes
(1)
Sample Type
Plasma
(4)
Serum
(4)
Tissue Homogenates
(1)
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.938 - 60 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Chicken
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Guinea pig
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Rabbit
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Sheep
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
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