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UCKL1 is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants.
Gene Name: | uridine-cytidine kinase 1-like 1 |
Synonyms: | UCKL1, Uridine kinase-like 1, URKL1, UCK1-LIKE, UCK1L, Uridine-cytidine kinase-like 1 |
Target Sequences: | NM_017859 NP_060329.2 Q9NWZ5 |
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