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UBN1 / Ubinuclein 1

ubinuclein 1

Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly.

Gene Name: ubinuclein 1
Synonyms: UBN1, HIRA-binding protein, Protein VT4, VT, Ubinuclein-1, VT4, Ubinuclein 1
Target Sequences: NM_016936 NP_058632.2 Q9NPG3

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Products
Antibodies (17)
Primary (17)
UBN1 / Ubinuclein 1 (17)
Human (17)
Mouse (7)
Rat (1)
Bat (1)
Bovine (4)
Chicken (1)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Hamster (1)
Horse (1)
Monkey (1)
Rabbit (4)
Zebrafish (1)
IHC (6)
IHC-P (1)
WB (12)
DB (1)
ELISA (5)
IF (3)
IP (2)
Peptide-ELISA (3)
rabbit (12)
mouse (4)
goat (1)
Product Group
IHCPlus (1)
IgG (14)
IgG1 (2)
monoclonal mc (4)
polyclonal pc (13)
UBN1-02 (2)
UBN1G12 (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (14)
aa974-1023 (4)
130-210 aa, Internal (1)
aa1084-1134 (1)
aa140-154 (1)
aa161-210 (1)
No (17)
UBN1 / Ubinuclein 1 Antibody - Anti-UBN1 / Ubinuclein 1 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal (aa161-210) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal (130-210 aa, Internal) Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
UBN1 / Ubinuclein 1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Ubinuclein antibody.
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
UBN1 / Ubinuclein 1 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using UBN1 Polyclonal Antibody at dilution of 1:75(×200)
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
UBN1 / Ubinuclein 1 Antibody - Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using UBN1 Polyclonal Antibody at dilution of 1:130(×200)
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
UBN1 / Ubinuclein 1 Antibody - Western blotting analysis of ubinuclein in nuclear fraction of HeLa cells. The monoclonal antibody UBN1-01 (lane A, B) detects ubinuclein 1 (165 kDa) and an 180 kDa protein - presumable ubinuclein 2. The antibody UBN1-02 (lane C, D) detects ubinuclein 1. Antibody dilution: A, C - 1 µg/ml; B, D - 5 µg/ml.
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UBN1 / Ubinuclein 1 Mouse anti-Human Monoclonal (UBN1-02) Antibody
Human
IP, WB
Unconjugated
0.1 mg/$337
UBN1 / Ubinuclein 1 Antibody - Western blot analysis of immunized recombinant protein, using anti-UBN1 monoclonal antibody.
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UBN1 / Ubinuclein 1 Mouse anti-Human Monoclonal (UBN1G12) Antibody
Human
DB, WB
Unconjugated
100 µg/$486
UBN1 / Ubinuclein 1 Antibody - Ubinuclein 1 Antibody in Western Blot (WB)
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UBN1 / Ubinuclein 1 Mouse anti-Human Monoclonal (UBN1-02) Antibody
Human
IP, WB
Unconjugated
100 µg/$447
UBN1 / Ubinuclein 1 Antibody - Western blot analysis Ubinuclein using LOVO cells whole cells lysates
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
UBN1 / Ubinuclein 1 Antibody - UBN1 antibody (1 ug/ml) staining of MOLT4 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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UBN1 / Ubinuclein 1 Goat anti-Human Polyclonal (aa140-154) Antibody
Chicken, Zebrafish, Horse, Bat, Rat, Hamster, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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UBN1 / Ubinuclein 1 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µg/$786
UBN1 / Ubinuclein 1 Antibody - Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal (aa974-1023) Antibody
Human
WB
Unconjugated
100 µl/$424
UBN1 / Ubinuclein 1 Antibody - Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal (aa974-1023) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Human, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
UBN1 / Ubinuclein 1 Antibody - Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal (aa974-1023) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Human, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
UBN1 / Ubinuclein 1 Antibody - Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal (aa974-1023) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Human, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
UBN1 / Ubinuclein 1 Antibody - Detection of Human Ubinuclein-1 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Ubinuclein-1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
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UBN1 / Ubinuclein 1 Rabbit anti-Human Polyclonal (aa1084-1134) Antibody
Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).