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DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing.
Gene Name: | transcription termination factor, RNA polymerase II |
Synonyms: | TTF2, Human factor 2, Transcription release factor 2, HuF2, Lodestar homolog, Lodestar protein |
Target Sequences: | NM_003594 NP_003585.3 Q9UNY4 |
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