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Newark, CA 94560
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TTDN1
M-phase specific PLK1 interacting protein
TTDN1 localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.
| Gene Name: | M-phase specific PLK1 interacting protein |
| Synonyms: | MPLKIP, ABHS, C7orf11, ORF20, Russell-Silver syndrome region, TTDN1 |
| Target Sequences: | NM_138701 NP_619646.1 Q8TAP9 |
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