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TTC19 is a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34 aa each. These repeats are found in a variety of organisms including bacteria, fungi and plants, and are involved in a variety of functions including protein-protein interactions. This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III. It has also been suggested that this protein plays a role in cytokinesis. Mutations in this gene cause mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene.
Gene Name: | tetratricopeptide repeat domain 19 |
Synonyms: | TTC19, TPR repeat protein 19 |
Target Sequences: | NM_017775 NP_060245.3 Q6DKK2 |
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