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Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.
Gene Name: | translocator protein (18kDa) |
Synonyms: | TSPO, BZRP, BPBS, IBP, MBR, MDRC, PBR, PBRS, PBS, PKBS, PTBR, Pk18, Translocator protein, Translocator protein (18kDa) |
Target Sequences: | NM_000714 NP_000705.2 P30536 |
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