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TSPAN4

tetraspanin 4

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: tetraspanin 4
Family/Subfamily: Tetraspan , not assigned-Tetraspan
Synonyms: TSPAN4, NAG-2, NAG2, Novel antigen 2, TM4SF7, TETRASPAN, Tetraspanin 4, TSPAN-4, Tetraspanin-4, Tetraspan TM4SF
Target Sequences: NM_003271 NP_003262.1 O14817

Publications (2)

1
Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation. Schmidt-Pogoda A, Strecker JK, Liebmann M, Massoth C, Beuker C, Hansen U, König S, Albrecht S, Bock S, Breuer J, Sommer C, Schwab N, Wiendl H, Klotz L, Minnerup J. PloS one. 2018 December;13:e0209871. [Full Text Article] [PubMed:30589884] [PMC:PMC6307724] Related Antibodies: LS-C496962.
2
Stroke induces disease-specific myeloid cells in the brain parenchyma and pia. Carolin Beuker , David Schafflick , Jan-Kolja Strecker , Michael Heming, Xiaolin Li, Jolien Wolbert, Antje Schmidt-Pogoda, Christian Thomas, Tanja Kuhlmann, Irene Aranda-Pardos, Noelia A-Gonzalez, Praveen Ashok Kumar, Yves Werner, Ertugrul Kilic, Dirk M Hermann, Heinz Wiendl, Ralf Stumm, Gerd Meyer Zu Hörste, Jens Minnerup. Nature communications. 2022 February;13:945. [Full Text Article] [PubMed:35177618] [PMC:PMC8854573] Related Antibodies: LS-B11508.

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Proteins (12)
Over-Expression Lysate (12)
TSPAN4 (12)
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Myc-DDK (Flag) (12)
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TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
25.9 kDa
20 µg/$150
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
25.9 kDa
20 µg/$150
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.9 kDa
20 µg/$150
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.9 kDa
20 µg/$150
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.12 kDa
20 µg/$150
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.9 kDa
20 µg/$150
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.9 kDa
100 µg/$494
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.9 kDa
100 µg/$494
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.9 kDa
100 µg/$494
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.9 kDa
100 µg/$494
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.9 kDa
100 µg/$494
TSPAN4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.12 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).