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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Name: | tetraspanin 4 |
Family/Subfamily: | Tetraspan , not assigned-Tetraspan |
Synonyms: | TSPAN4, NAG-2, NAG2, Novel antigen 2, TM4SF7, TETRASPAN, Tetraspanin 4, TSPAN-4, Tetraspanin-4, Tetraspan TM4SF |
Target Sequences: | NM_003271 NP_003262.1 O14817 |
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