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TSHB / TSH-Beta

thyroid stimulating hormone, beta

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: thyroid stimulating hormone, beta
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: TSHB, Thyrotropin alfa, Thyrotropin beta subunit, TSH Beta, TSH-B, Thyrotropin beta chain, Thyrotropin subunit beta, TSH-BETA, CHNG4
Target Sequences: NM_000549 NP_000540.2 P01222

Publications (2)

1
MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression. Zhang Z, Florez S, Gutierrez-Hartmann A, Martin JF, Amendt BA. The Journal of biological chemistry. 2010 285:34718-28. (IHC-P; Mouse) [PubMed:20807761] [PMC:PMC2966087]
2
Thyroid hormone receptor ß sumoylation is required for thyrotropin regulation and thyroid hormone production. Sujie Ke , Yan-Yun Liu, Rajendiran Karthikraj, Kurunthachalam Kannan, Jingjing Jiang , Kiyomi Abe , Anna Milanesi, Gregory A Brent. JCI insight. 2021 Aug;6:e149425. [Full Text Article] [PubMed:34237030] [PMC:PMC8410017] Related Antibodies: LS-C334949.

☰ Filters
Antibodies (121)
Proteins (10)
ELISA Kits (8)
Competitive EIA (2)
Custom (3)
Over-Expression Lysate (2)
Primary (121)
Recombinant (8)
Sandwich (3)
TSHB / TSH-Beta (139)
Human (94)
Mouse (25)
Rat (7)
Chicken (4)
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IHC (16)
IHC-P (1)
WB (47)
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ELISA (88)
ICC (8)
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rabbit (39)
mouse (67)
goat (5)
chicken (4)
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monoclonal mc (73)
polyclonal pc (48)
154 (1)
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1D12G1 (1)
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HRP Conjugated (17)
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Unconjugated (41)
aa21-138 (16)
aa20-138 (8)
aa58-86 (7)
aa21-132 (4)
aa20-134 (3)
No (138)
Yes (1)
Plasma (5)
Serum (5)
Tissue Homogenates (2)
10His, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
6His, N-terminus + Myc, C-terminus (1)
His (1)
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Human (4)
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E. coli (6)
HEK 293 Cells (2)
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Purified (3)
TSHB / TSH-Beta Antibody - Immunohistochemistry of paraffin-embedded human prostate.
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TSHB / TSH-Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
TSHB / TSH-Beta Antibody
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TSHB / TSH-Beta Rabbit anti-Mouse Polyclonal (aa21-138) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
TSHB / TSH-Beta Antibody
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TSHB / TSH-Beta Rabbit anti-Mouse Polyclonal (aa21-138) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
TSHB / TSH-Beta Antibody
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TSHB / TSH-Beta Rabbit anti-Mouse Polyclonal (aa21-138) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
TSHB / TSH-Beta Antibody
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TSHB / TSH-Beta Rabbit anti-Mouse Polyclonal (aa21-138) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
TSHB / TSH-Beta Antibody
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TSHB / TSH-Beta Rabbit anti-Mouse Polyclonal (aa21-138) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
TSHB / TSH-Beta ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
0.156 - 10 µIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TSHB / TSH-Beta Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
19.9 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
TSHB / TSH-Beta Antibody - Western blot of recombinant TSHB / TSH-Beta.
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TSHB / TSH-Beta Mouse anti-Mouse Monoclonal (aa21-138) Antibody
Mouse
ICC, IP, WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331
TSHB / TSH-Beta Antibody - Immunohistochemistry of paraffin-embedded mouse lung tissue slide using TSH beta antibody at dilution of 1:100
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TSHB / TSH-Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
TSHB / TSH-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 mIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$441
TSHB / TSH-Beta ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
0.156 - 10 µIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Select
TSHB / TSH-Beta Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
IHC, WB
Unconjugated
20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439
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TSHB / TSH-Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
TSHB / TSH-Beta Antibody - Formalin-fixed and paraffin-embedded human breast carcinoma reacted with TSHB Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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TSHB / TSH-Beta Rabbit anti-Human Polyclonal (aa58-86) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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TSHB / TSH-Beta Goat anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
1 mg/$688
TSHB / TSH-Beta Antibody - Western blot analysis of extracts of various cell lines, using TSHB antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
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TSHB / TSH-Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
TSHB / TSH-Beta Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, ID, IHC, IP, WB
Unconjugated
1 mg/$473
Select
TSHB / TSH-Beta Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, ID, IHC, IP, WB
Unconjugated
0.5 mg/$797
TSHB / TSH-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$441
Select
E. coli
6His, N-terminus
14.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
TSHB / TSH-Beta Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus + Myc, C-terminus
16.4 kDa
100 µg/$570; 20 µg/$395; 1 mg/$1,973
TSHB / TSH-Beta Protein
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E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
Select
TSHB / TSH-Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
TSHB / TSH-Beta Sheep anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$697
Viewing 1-25 of 139 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).