TRXR1 / TXNRD1

thioredoxin reductase 1

TRXR1 / TXNRD1 is a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

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Products

Proteins (9)

Type

Recombinant (9)

Target

TRXR1 / TXNRD1 (9)

Publications

No (9)

Tag

GST (1)

His (3)

His, N-Terminal (1)

His-SUMO (1)

His-T7 (2)

Myc-DDK (Flag) (1)

Species

Human (7)

Mouse (1)

Rat (1)

Source

E. coli (7)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

Biologically Active

Biologically active (1)

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Human TRXR1 / TXNRD1 Protein (Recombinant His) - LS-G793

Source:

E. coli

Tag:

His

Biological Activity:

Biologically active

Price:

100 µg/$342; 20 µg/$254

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Human TRXR1 / TXNRD1 Protein (Recombinant His, N-Terminal) - LS-G144383

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

60.2 kDa

Price:

50 µg/$419

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Human TRXR1 / TXNRD1 Protein (Recombinant GST) (Full Length) - LS-G30805

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

80.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TRXR1 / TXNRD1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67111

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.6 kDa

Price:

20 µg/$1,107

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Human TRXR1 / TXNRD1 Protein (Recombinant His-SUMO) (aa1-497) - LS-G21658

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

58.61 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse TRXR1 / TXNRD1 Protein (Recombinant His-T7) (aa374-577) - LS-G12663

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.1 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Rat TRXR1 / TXNRD1 Protein (Recombinant His-T7) (aa208-433) - LS-G12667

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.0 kDa

Price:

50 µg/$472; 10 µg/$286; 200 µg/$942; 100 µg/$752; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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Human TRXR1 / TXNRD1 Protein (Recombinant His) (Tyr161-Cys647) - LS-G97996

Source:

E. coli

Tag:

His

Molecular Weight:

55 kDa

Price:

100 µg/$793

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Human TRXR1 / TXNRD1 Protein (Recombinant His) - LS-G1070

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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