TRPV6

transient receptor potential cation channel, subfamily V, member 6

Calcium selective cation channel probably involved in Ca2+ uptake in various tissues, including Ca2+ reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca2+-dependent and a slower Ca2+-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg2+ in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

TRPV6 (3)

Publications

No (3)

Tag

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

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Human TRPV6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92753

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83 kDa

Price:

20 µg/$215

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TRPV6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101586

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83 kDa

Price:

100 µg/$710

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Human TRPV6 Protein (Recombinant His-T7) (aa578-725) - LS-G25658

Source:

E. coli

Tag:

His-T7

Molecular Weight:

21.2 kDa

Price:

10 µg/$272; 50 µg/$387; 100 µg/$620; 200 µg/$772; 1 mg/$1,834; 500 µg/$1,393; 5 mg/$3,089

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