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TRPC6

transient receptor potential cation channel, subfamily C, member 6

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.

Gene Name: transient receptor potential cation channel, subfamily C, member 6
Family/Subfamily: Ion Channel , Calcium channel - TRP
Synonyms: TRPC6, Transient receptor protein 6, Trrp6, TRP-6, TRP6, FSGS2
Target Sequences: NM_004621 NP_004612.2 Q9Y210

Publications (1)

1
Modulation of Calcium Transients in Cardiomyocytes by Transient Receptor Potential Canonical 6 Channels. Azmi A Ahmad, Molly E Streiff, Chris Hunter, Frank B Sachse. Frontiers in physiology. 2020 Feb;11:44. [Full Text Article] [PubMed:32116757] [PMC:PMC7033547] Related Antibodies: LS-C19628.

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Proteins (2)
Recombinant (2)
TRPC6 (2)
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GST, N-terminus (1)
His-S (1)
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E. coli (1)
Wheat Germ Extract (1)
TRPC6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TRPC6 Protein - Recombinant  Transient Receptor Potential Cation Channel Subfamily C, Member 6 By SDS-PAGE
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E. coli
His-S
25 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).