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Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Gene Name: | transient receptor potential cation channel, subfamily C, member 1 |
Family/Subfamily: | Ion Channel , Calcium channel - TRP |
Synonyms: | TRPC1, HTRP-1, TRP1, TRP-1, Trrp1, Transient receptor protein 1 |
Target Sequences: | NM_003304 NP_003295.1 P48995 |
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