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TRIM8 / GERP is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.
Gene Name: | tripartite motif containing 8 |
Family/Subfamily: | Tripartite Motif |
Synonyms: | TRIM8, RING finger protein 27, Tripartite motif-containing 8, Tripartite motif containing 8, GERP, RNF27, Tripartite motif protein TRIM8 |
Target Sequences: | NM_030912 NP_112174.2 Q9BZR9 |
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