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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene Name: | tripartite motif containing 26 |
Family/Subfamily: | Tripartite Motif |
Synonyms: | TRIM26, Acid finger protein, ZNF173, RING finger protein 95, RNF95, Tripartite motif containing 26, Zinc finger protein 173, Tripartite motif-containing 26 |
Target Sequences: | NM_003449 NP_003440.1 Q12899 |
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