Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Gene Name: | tripartite motif containing 23 |
Family/Subfamily: | Tripartite Motif |
Synonyms: | TRIM23, ARFD1, ARD1, ARF domain protein 1, RING finger protein 46, RNF46, Tripartite motif-containing 23, GTP-binding protein ARD-1, Tripartite motif containing 23 |
Target Sequences: | NM_001656 NP_001647.1 P36406 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.