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TREML1 / TLT1 is a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants
Gene Name: | triggering receptor expressed on myeloid cells-like 1 |
Synonyms: | TREML1, DJ238O23.3, GLTL1825, TLT-1, Trem-like transcript 1 protein, TLT1, PRO3438 |
Target Sequences: | Q86YW5 Q86YW5 |
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