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Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
Gene Name: | triggering receptor expressed on myeloid cells 1 |
Synonyms: | TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1 |
Target Sequences: | NM_018643 NP_061113.1 Q9NP99 |
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