TRB3 / TRIB3

tribbles pseudokinase 3

Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.

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Products

ELISA Kits (5)

Type

Custom (2)

Sandwich (3)

Target

TRB3 / TRIB3 (5)

Reactivity

Human (2)

Mouse (1)

Rat (1)

Format

96-Well Strip Plate (5)

Publications

No (5)

Sample Type

Cell Culture Supernatants (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

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Human TRB3 / TRIB3 (Sandwich ELISA) ELISA Kit - LS-F13483

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Mouse TRB3 / TRIB3 (Sandwich ELISA) ELISA Kit - LS-F20585

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human TRB3 / TRIB3 (Sandwich ELISA) ELISA Kit - LS-F34162

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Bovine TRB3 / TRIB3 (Custom ELISA) ELISA Kit - LS-F20584

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat TRB3 / TRIB3 (Custom ELISA) ELISA Kit - LS-F20586

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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