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Necessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Gene Name: | translocation associated membrane protein 2 |
Synonyms: | TRAM2, KIAA0057, TRAM-like protein |
Target Sequences: | D31762 BAA06540.2 Q15035 |
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