TRAIL-R3 / DCR1

tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts were expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.

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Products

ELISA Kits (5)

Type

Custom (2)

Sandwich (3)

Target

TRAIL-R3 / DCR1 (5)

Reactivity

Human (5)

Format

96-Well Microplate (1)

96-Well Strip Plate (4)

Publications

No (5)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

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Human TRAIL-R3 / DCR1 (Sandwich ELISA) ELISA Kit - LS-F201

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

16.38 - 1600 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Human TRAIL-R3 / DCR1 (Sandwich ELISA) ELISA Kit - LS-F39870

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

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Human TRAIL-R3 / DCR1 (Custom ELISA) ELISA Kit - LS-F56649

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$822

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Human TRAIL-R3 / DCR1 (Sandwich ELISA) ELISA Kit - LS-F55597

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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Human TRAIL-R3 / DCR1 (Custom ELISA) ELISA Kit - LS-F20598

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$585

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