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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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TRAFD1 / FLN29
TRAF-type zinc finger domain containing 1
Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
| Gene Name: | TRAF-type zinc finger domain containing 1 |
| Synonyms: | TRAFD1, FLN29, Protein FLN29, FLN29 gene product |
| Target Sequences: | NM_006700 NP_006691.1 O14545 |
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