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TPP1 / CLN2

tripeptidyl peptidase I

TPP1 / CLN2 is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Gene Name: tripeptidyl peptidase I
Family/Subfamily: Protease , Serine S53
Synonyms: TPP1, CLN2, GIG1, LPIC, LINCL, TPP-I, Tripeptidyl aminopeptidase, Tripeptidyl peptidase I, Tripeptidyl-peptidase 1, Tripeptidyl-peptidase I, TPP-1, Growth-inhibiting protein 1
Target Sequences: NM_000391 NP_000382.3 O14773

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Products
ELISA Kits (7)
Custom (1)
Sandwich (5)
Sandwich CLIA (1)
TPP1 / CLN2 (7)
Human (5)
Mouse (1)
Monkey (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (3)
No (7)
Cell Culture Supernatants (1)
Cell Lysates (1)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (2)
Serum (3)
Tissue Homogenates (2)
TPP1 / CLN2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
TPP1 / CLN2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$748
TPP1 / CLN2 ELISA Kit
Select
Sandwich
Human
156 - 10000 pg/ml
Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$699
TPP1 / CLN2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
TPP1 / CLN2 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
TPP1 / CLN2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
TPP1 / CLN2 ELISA Kit
Select
Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$610
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).