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TPO / Thyroid Peroxidase

thyroid peroxidase

TPO / Thyroid Peroxidase is a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.

Gene Name: thyroid peroxidase
Synonyms: TPO, MSA, Thyroid microsomal antigen, Thyroid peroxidase, TDH2A, TPX, Thyroperoxidase
Target Sequences: NM_000547 NP_000538.3 P07202

☰ Filters
Products
Proteins (13)
Over-Expression Lysate (2)
Recombinant (11)
TPO / Thyroid Peroxidase (13)
No (13)
GST (1)
GST, N-terminus (1)
His (6)
His,C-terminus (1)
Myc-DDK (Flag) (3)
Human (9)
Mouse (2)
Rat (1)
293T Cells (1)
Baculovirus (1)
E. coli (4)
HEK 293 Cells (3)
Insect Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (1)
Low endotoxin level (2)
Select
Insect Cells
None
100-110 kDa
100 µg/$1,380
Select
E. coli
His
21.5 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
TPO / Thyroid Peroxidase Protein - Recombinant Thyroid Peroxidase By SDS-PAGE
Select
E. coli
His
23.9 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
93.8 kDa
100 µg/$997
TPO / Thyroid Peroxidase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
102.8 kDa
20 µg/$150
TPO / Thyroid Peroxidase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
102.8 kDa
100 µg/$494
TPO / Thyroid Peroxidase Protein
Select
HEK 293 Cells
His,C-terminus
92.6KDa
20 µg/$1,107
Select
E. coli
129 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
14.3 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
TPO / Thyroid Peroxidase Protein - Recombinant Thyroid Peroxidase By SDS-PAGE
Select
E. coli
His
20.5 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
TPO / Thyroid Peroxidase Protein
Select
Yeast
His
17.9 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
TPO / Thyroid Peroxidase Protein - 12.5% SDS-PAGE of human TPO stained with Coomassie Blue
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Wheat Germ Extract
GST
129.3 kDa
2 µg/$439
TPO / Thyroid Peroxidase Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TPO / Thyroid Peroxidase Protein - Purified recombinant protein TPO was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
102.8 kDa
20 µg/$1,107
Viewing 1-13 of 13 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).