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Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC.
Gene Name: | telomerase-associated protein 1 |
Synonyms: | TEP1, p80 telomerase homolog, Telomerase protein 1, TLP1, TROVE domain family, member 1, TROVE1, VAULT2, p240, Telomerase protein component 1, TP1 |
Target Sequences: | NM_007110 NP_009041.2 Q99973 |
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