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Some high-mobility group (HMG) box proteins contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.
Gene Name: | thymocyte selection-associated high mobility group box |
Synonyms: | TOX, KIAA0808, TOX1 |
Target Sequences: | NM_014729 NP_055544.1 O94900 |
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