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TOR1AIP1 / LAP1

torsin A interacting protein 1

Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.

Gene Name: torsin A interacting protein 1
Synonyms: TOR1AIP1, LAP1B, Lamin-associated protein 1B, LAP1, Torsin A interacting protein 1
Target Sequences: Q5JTV8 Q5JTV8

Publications (1)

1
Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy. Fichtman B, Zagairy F, Biran N, Barsheshet Y, Chervinsky E, Ben Neriah Z, Shaag A, Assa M, Elpeleg O, Harel A, Spiegel R. Nature communications. 2019 February;10:605. [Full Text Article] [PubMed:30723199] [PMC:PMC6363790] Related Antibodies: LS-C288839.

☰ Filters
Antibodies (13)
Proteins (4)
Over-Expression Lysate (2)
Primary (13)
Recombinant (2)
TOR1AIP1 / LAP1 (17)
Human (13)
Mouse (3)
Rat (2)
IHC (5)
IHC-P (1)
WB (9)
ELISA (5)
IF (1)
IP (3)
Peptide-ELISA (3)
rabbit (13)
Product Group
IHCPlus (1)
IgG (11)
polyclonal pc (13)
Unconjugated (13)
aa275-325 (2)
400-480 aa, Internal (1)
Internal (1)
N-Terminus (1)
aa175-225 (1)
aa416-465 (1)
aa431-480 (1)
No (16)
Yes (1)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal (aa175-225) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
TOR1AIP1 / LAP1 Antibody - Anti-TOR1AIP1 Antibody (N-Term) at 1:2000 dilution + mouse testis lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 66 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$393
TOR1AIP1 / LAP1 Antibody - Western blot analysis of TOR1AIP1 expression in HeLa (A) whole cell lysates.
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TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IP, WB
Unconjugated
100 µl/$299
TOR1AIP1 / LAP1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal (400-480 aa, Internal) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TOR1AIP1 / LAP1 Protein - Purified recombinant protein TOR1AIP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
66.1 kDa
20 µg/$1,107
TOR1AIP1 / LAP1 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TOR1AIP1 / LAP1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using TOR1AIP1 Polyclonal Antibody at dilution of 1:70(×200)
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TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TOR1AIP1 / LAP1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using TOR1AIP1 Polyclonal Antibody at dilution of 1:60(×200)
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TOR1AIP1 / LAP1 Antibody - Detection of Human LAP1B by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-LAP1B used at a dilution of 1:200 (1 Detection: DAB.
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal (aa275-325) Antibody
Human
IHC, IP
Unconjugated
10 µg/$295; 100 µl/$514
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal (aa431-480) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TOR1AIP1 / LAP1 Antibody - Western blot analysis of the lysates from COLO205 cells using TOR1AIP1 antibody.
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal (aa416-465) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TOR1AIP1 / LAP1 Antibody - Detection of Human LAP1B Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-LAP1B used at a dilution of 1:250.
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal (aa275-325) Antibody
Human
IHC
Unconjugated
2.5 µg/$295; 100 µl/$532
Select
TOR1AIP1 / LAP1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$386
TOR1AIP1 / LAP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
66.1 kDa
20 µg/$215
TOR1AIP1 / LAP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
66.1 kDa
100 µg/$710
TOR1AIP1 / LAP1 Protein - 12.5% SDS-PAGE of human TOR1AIP1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
78.8 kDa
2 µg/$439
Viewing 1-17 of 17 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).