TNR / Tenascin R

tenascin R

Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance.

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Products

ELISA Kits (14)

Type

Custom (4)

Sandwich (10)

Target

TNR / Tenascin R (14)

Reactivity

Human (6)

Mouse (1)

Rat (1)

Chicken (2)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (11)

Publications

No (14)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (4)

Serum (5)

Tissue Homogenates (1)

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Human TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F27286

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Mouse TNR / Tenascin R (Custom ELISA) ELISA Kit - LS-F16896

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human TNR / Tenascin R (Custom ELISA) ELISA Kit - LS-F16897

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Chicken TNR / Tenascin R (Custom ELISA) ELISA Kit - LS-F16898

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Rat TNR / Tenascin R (Custom ELISA) ELISA Kit - LS-F16895

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F37957

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Chicken TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F48410

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F48411

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F48412

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F48413

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F48414

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Human TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F50091

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.2 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$610

Select

Human TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F57351

Type:

Sandwich

Reactivity:

Human

Range:

156 - 10000 pg/ml

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$699

Select

Human TNR / Tenascin R (Sandwich ELISA) ELISA Kit - LS-F74453

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$564

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