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TNNI3 / Cardiac Troponin I
troponin I type 3 (cardiac)
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
| Gene Name: | troponin I type 3 (cardiac) |
| Synonyms: | TNNI3, CTnI, CMD1FF, CMD2A, RCM1, Troponin I, cardiac, Troponin I, cardiac muscle, Troponin I type 3 (cardiac), Cardiac troponin I, CMH7 |
| Target Sequences: | NM_000363 NP_000354.4 P19429 |
Publications (5)
1
Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance. Kirthana Ganeshan, Joni Nikkanen, Kevin Man, Yew Ann Leong, Yoshitaka Sogawa, J Alan Maschek, Tyler Van Ry, D Nyasha Chagwedera, James E Cox, Ajay Chawla. Cell. 2019 April;177:399-413.e12. [Full Text Article]
[PubMed:30853215]
[PMC:PMC6456449]
2
MR-guided pulsed focused ultrasound improves mesenchymal stromal cell homing to the myocardium. Kee W Jang, Tsang-Wei Tu, Robert B Rosenblatt, Scott R Burks, Joseph A Frank. Journal of cellular and molecular medicine. 2020 October; [Full Text Article]
[PubMed:33067927]
[PMC:PMC7701528]
3
Assessment of inflammatory markers and mitochondrial factors in a rat model of sepsis-induced myocardial dysfunction. Xiao-Mei Zeng, De-Hong Liu, Yong Han, Zhi-Qiang Huang, Ji-Wen Zhang, Qun Huang. American journal of translational research. 2020 April;12:901-911.
[PubMed:32269722]
[PMC:PMC7137057]
☰ Filters
Products
Proteins
(18)
Type
Over-Expression Cell Culture Supernatant
(1)
Over-Expression Lysate
(3)
Recombinant
(13)
Target
TNNI3 / Cardiac Troponin I
(18)
Publications
No
(18)
Tag
10His, N-terminus + Myc, C-terminus
(1)
6His, N-terminus
(4)
6His-SUMO, N-terminus
(1)
DDK,C-terminus
(1)
GST
(1)
GST, N-terminus
(1)
His
(1)
His, N-Terminal
(2)
His-T7
(2)
Myc-DDK (Flag)
(3)
Species
Bovine
(1)
Dog
(1)
Human
(11)
Mouse
(2)
Pig
(1)
Rat
(1)
Source
293T Cells
(1)
E. coli
(10)
HEK 293 Cells
(4)
Sf9 Cells
(1)
Wheat Germ Extract
(2)
Purification
Purified
(5)
E. coli
His, N-Terminal
25.8 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
E. coli
6His, N-terminus
26 kDa
1 mg/$2,029; 10 µg/$253; 50 µg/$308
E. coli
His, N-Terminal
25.7 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
E. coli
His
24.6 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
E. coli
6His, N-terminus
26.1 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 200 µg/$484
E. coli
His-T7
27.7 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
HEK 293 Cells
Myc-DDK (Flag)
23.8 kDa
20 µg/$1,107
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
E. coli
His-T7
27.6 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
HEK 293 Cells
6His, N-terminus
26 kDa
200 µl/$283
HEK 293 Cells
6His, N-terminus
26 kDa
100 µg/$298
Wheat Germ Extract
GST
48.73 kDa
2 µg/$439
293T Cells
Myc-DDK (Flag)
23.8 kDa
20 µg/$215
Sf9 Cells
DDK,C-terminus
23.8 kDa
20 µg/$677
HEK 293 Cells
Myc-DDK (Flag)
23.8 kDa
100 µg/$710
E. coli
None
24 kDa
10 µg/$326; 50 µg/$406; 1000 µg/$2,576
E. coli
10His, N-terminus + Myc, C-terminus
39.0 kDa
1 mg/$1,679; 100 µg/$598; 20 µg/$405
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