TNFSF9 / CD137L

tumor necrosis factor (ligand) superfamily, member 9

TNFSF9 / CD137L is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

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ELISA Kits (6)

Type

Cell-Based (1)

Custom (2)

Sandwich (3)

Target

TNFSF9 / CD137L (6)

Reactivity

Human (5)

Mouse (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (4)

Publications

No (6)

Sample Type

Adherent Cell Cultures (1)

Cell Culture Supernatants (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

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Human TNFSF9 / CD137L (Sandwich ELISA) ELISA Kit - LS-F8841

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

7.81 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$730

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Human TNFSF9 / CD137L (Sandwich ELISA) ELISA Kit - LS-F49840

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.2 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$559

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Human TNFSF9 / CD137L (Cell-Based ELISA) ELISA Kit - LS-F3101

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Mouse TNFSF9 / CD137L (Custom) ELISA Kit - LS-F65678

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$669

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Human TNFSF9 / CD137L (Custom) ELISA Kit - LS-F65487

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Price:

1 Plate/$669

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Human TNFSF9 / CD137L (Sandwich ELISA) ELISA Kit - LS-F52742

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$897

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