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TNFSF13 / APRIL

tumor necrosis factor (ligand) superfamily, member 13

TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

Gene Name: tumor necrosis factor (ligand) superfamily, member 13
Family/Subfamily: TNF , not assigned-TNF
Synonyms: TNFSF13, APRIL, CD256, CD256 antigen, TALL-2, TALL2, ZTNF2, TNF-related death ligand 1, TRDL-1, UNQ383/PRO715
Target Sequences: NM_003808 NP_003799.1 O75888

Publications (3)

1
Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia. Robak OH, Heimesaat MM, Kruglov AA, Prepens S, Ninnemann J, Gutbier B, Reppe K, Hochrein H, Suter M, Kirschning CJ, Marathe V, Buer J, Hornef MW, Schnare M, Schneider P, Witzenrath M, Bereswill S, Steinhoff U, Suttorp N, Sander LE, Chaput C, Opitz B. The Journal of clinical investigation. 2018 August;128:3535-3545. [Full Text Article] [PubMed:29771684] [PMC:PMC6063483]
2
Soluble a-proliferation-inducing ligand (sAPRIL), a novel serum biomarker predicting the recurrence and metastasis of pancreatic adenocarcinoma after surgery. Han L, Zhang W, Song F, Guo Y, Guo K, Zhou W. Molecular medicine reports. 2014 October;10:1978-1984. [Full Text Article] [PubMed:25110120]
3
Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas. Guadagnoli M, Kimberley FC, Phan U, Cameron K, Vink PM, Rodermond H, Eldering E, Kater AP, van Eenennaam H, Medema JP. Blood. 2011 Jun;117:6856-65. [Full Text Article] [PubMed:21543761] Related Antibodies: LS-C18659, LS-C18687, LS-C18658.

☰ Filters
Antibodies (98)
Proteins (27)
ELISA Kits (12)
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Primary (98)
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TNFSF13 / APRIL (137)
Human (65)
Mouse (38)
Rat (32)
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monoclonal mc (13)
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Aprily-1 (1)
Aprily-8 (1)
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aa105-250 (17)
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120-200 aa, Internal (1)
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Biologically active (3)
Select
TNFSF13 / APRIL Mouse anti-Human Monoclonal (aa93-233) (Aprily-8) Antibody
Human
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$530
TNFSF13 / APRIL Antibody - Anti-APRIL antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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TNFSF13 / APRIL Rabbit anti-Human Polyclonal (aa151-200) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
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TNFSF13 / APRIL Mouse anti-Human Monoclonal (aa93-233) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$563
TNFSF13 / APRIL Antibody - Anti-APRIL antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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TNFSF13 / APRIL Rabbit anti-Human Polyclonal (aa1-17) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$440
TNFSF13 / APRIL Antibody - Anti-APRIL antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
TNFSF13 / APRIL ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$715
TNFSF13 / APRIL ELISA Kit
Select
Sandwich
96-Well Microplate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
TNFSF13 / APRIL ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
TNFSF13 / APRIL ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
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TNFSF13 / APRIL Mouse anti-Human Monoclonal (Aprily-1) Antibody
Human
Flo, IP, WB
Unconjugated
100 µg/$538
TNFSF13 / APRIL Antibody - Anti-APRIL antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
TNFSF13 / APRIL ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Select
TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
TNFSF13 / APRIL Antibody - Biotinylated Anti-Human APRIL Sandwich ELISA
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TNFSF13 / APRIL Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
TNFSF13 / APRIL Protein
Select
High Five Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.3 kDa
2 µg/$268; 10 µg/$349
TNFSF13 / APRIL Antibody - Western blot of recombinant TNFSF13 / APRIL.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFSF13 / APRIL Rabbit anti-Human Polyclonal (aa105-250) (APC) Antibody
Mouse, Rat, Human
WB
APC Conjugated
100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325
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TNFSF13 / APRIL Rat anti-Human Monoclonal (aa105-250) Antibody
Mouse, Human
ELISA, Flo, ICC
Unconjugated
100 µg/$550
TNFSF13 / APRIL Antibody - Detection limit for recombinant GST tagged TNFSF13 is 1 ng/ml as a capture antibody.
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TNFSF13 / APRIL Mouse anti-Human Monoclonal (4A11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
TNFSF13 / APRIL Antibody - 1:100 staining human colon tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TNFSF13 / APRIL ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
5 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
TNFSF13 / APRIL Protein - Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 13 By SDS-PAGE
Select
E. coli
His
19.4 kDa
10 µg/$295; 50 µg/$532; 100 µg/$850; 200 µg/$1,049; 1 mg/$2,215; 500 µg/$1,733; 5 mg/$3,711; 2 mg/$2,407
Select
TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$460; 100 µg/$584
TNFSF13 / APRIL Antibody - Immunohistochemical analysis of CD256 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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TNFSF13 / APRIL Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
TNFSF13 / APRIL Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using TALL-2 antibody.
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TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
TNFSF13 / APRIL Antibody - Western blot of HeLa cell lysate using TALL-2 Antibody
Select
TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
Viewing 1-25 of 137 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).