TNFSF10 / TRAIL

tumor necrosis factor (ligand) superfamily, member 10

TNFSF10 / TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

ELISA Kits (33)

Type

Cell-Based (1)

Custom (1)

Development Kit (3)

Sandwich (24)

Sandwich CLIA (4)

Target

TNFSF10 / TRAIL (33)

Reactivity

Human (13)

Mouse (9)

Rat (5)

Chicken (1)

Dog (1)

Monkey (2)

Porcine (1)

Rabbit (1)

Product Group

DevKit Core (1)

DevKit DuoPlus (2)

Format

1000 Wells (1)

12 x 8-Well Microstrips (4)

96-Well Microplate (7)

96-Well Strip Plate (19)

Antibody Pair and Standard (2)

Publications

No (32)

Yes (1)

Sample Type

Adherent Cell Cultures (1)

Cell Culture Supernatants (10)

Cell Lysates (10)

Cerebrospinal Fluid (1)

Plasma (24)

Saliva (1)

Serum (24)

Tissue Homogenates (12)

Urine (1)

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Human TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F967

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$414

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Rat TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F23243

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F23115

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F296

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

2 - 600 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Human TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F2563

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Saliva, Serum

Price:

1 Plate/$699

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Human TNFSF10 / TRAIL (Cell-Based ELISA) ELISA Kit - LS-F3115

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F3678

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

40.96 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Dog TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F6428

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Dog

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$748

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Rat TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F6429

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

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Mouse TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F6410

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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Human TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F12789

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

46.9 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

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Mouse TNFSF10 / TRAIL (Custom ELISA) ELISA Kit - LS-F13845

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse TNFSF10 / TRAIL (CLIA) ELISA Kit - LS-F30956

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

7.813 - 500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Rat TNFSF10 / TRAIL (CLIA) ELISA Kit - LS-F40615

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

7.813 - 500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human TNFSF10 / TRAIL (CLIA) ELISA Kit - LS-F30010

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

7.813 - 500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F33428

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

DevKit Core Human TNFSF10 / TRAIL ELISA Development Kit - LS-F31215

Type:

Development Kit

Format:

1000 Wells

Reactivity:

Human

Range:

16 - 1000 pg/ml

Detection:

Colorimetric - 405nm (ABTS)

Price:

1 Test/$540

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Human TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F51198

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cerebrospinal Fluid, Plasma, Serum, Urine

Price:

1 Plate/$822

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Rat TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F54040

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$968

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DevKit DuoPlus Mouse TNFSF10 / TRAIL ELISA Development Kit - LS-F71666

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,207; 1000 Wells/$1,787

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Rat TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F56096

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F56125

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Monkey TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F56135

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F55219

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$749

Select

Porcine TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F48864

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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