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TNFRSF9 / 4-1BB / CD137

tumor necrosis factor receptor superfamily, member 9

TNFRSF9 / 4-1BB / CD137 is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Gene Name: tumor necrosis factor receptor superfamily, member 9
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF9, 4-1BB ligand receptor, 4-1BB, CD137 antigen, CD137, Homolog of mouse 4-1BB, ILA, Receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CDw137
Target Sequences: NM_001561 NP_001552.2 Q07011

Publications (2)

1
Progression of benign prostatic hyperplasia is associated with pro-inflammatory mediators and chronic activation of prostate-infiltrating lymphocytes. Norström MM, Rådestad E, Sundberg B, Mattsson J, Henningsohn L, Levitsky V, Uhlin M. Oncotarget. 2016 7:23581-93. (Flo, ELISA; Human) [Full Text Article] [PubMed:26993768] [PMC:PMC5029649]
2
CD137 (4-1BB) Engagement Fine-Tunes Synergistic IL-15- and IL-21-Driven NK Cell Proliferation. Laurent Vidard, Christine Dureuil, Jérémy Baudhuin, Lionel Vescovi, Laurence Durand, Véronique Sierra, Eric Parmantier. Journal of immunology (Baltimore, Md. : 1950). 2019 August;203:676-685. [Full Text Article] [PubMed:31201235]

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TNFRSF9 / 4-1BB / CD137 (14)
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TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
16 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich
96-Well Microplate
Human
12.29 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$760
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich
96-Well Microplate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
8 - 500 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$562
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Development Kit
1000 Wells
Human
16 - 2000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Custom
96-Well Microplate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$610
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$897
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
TNFRSF9 / 4-1BB / CD137 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).