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TNFRSF18 / GITR

tumor necrosis factor receptor superfamily, member 18

TNFRSF18 / GITR is a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene Name: tumor necrosis factor receptor superfamily, member 18
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF18, AITR, CD357, CD357 antigen, GITR, GITR-D
Target Sequences: NM_004195 NP_004186.1 Q9Y5U5

Publications (1)

1
Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states. Zhou Z, Song X, Berezov A, Zhang G, Li Y, Zhang H, Murali R, Li B, Greene MI. Proceedings of the National Academy of Sciences of the United States of America. 2008 105:5465-70. [PubMed:18378892] [PMC:PMC2291095] Related Antibodies: LS-C41004.

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Products
ELISA Kits (12)
Custom (4)
Sandwich (8)
TNFRSF18 / GITR (12)
Human (7)
Mouse (5)
96-Well Microplate (4)
96-Well Strip Plate (7)
No (12)
Cell Culture Supernatants (5)
Cell Lysates (2)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (7)
Serum (8)
Tissue Homogenates (2)
TNFRSF18 / GITR ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
TNFRSF18 / GITR ELISA Kit
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Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
TNFRSF18 / GITR ELISA Kit
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Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
TNFRSF18 / GITR ELISA Kit
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Sandwich
96-Well Microplate
Human
13.7 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
TNFRSF18 / GITR ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$624
TNFRSF18 / GITR ELISA Kit
Select
Custom
96-Well Microplate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$559
TNFRSF18 / GITR ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
1 Plate/$669
TNFRSF18 / GITR ELISA Kit
Select
Custom
96-Well Strip Plate
Human
1 Plate/$669
TNFRSF18 / GITR ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$822
TNFRSF18 / GITR ELISA Kit
Select
Sandwich
Human
62.5 - 4000 pg/ml
Cell Culture Supernatants, Cell Lysates, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$699
TNFRSF18 / GITR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
TNFRSF18 / GITR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$822
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).