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TNFRSF18 / GITR
tumor necrosis factor receptor superfamily, member 18
TNFRSF18 / GITR is a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
| Gene Name: | tumor necrosis factor receptor superfamily, member 18 |
| Family/Subfamily: | TNF Receptor , not assigned-TNF Receptor |
| Synonyms: | TNFRSF18, AITR, CD357, CD357 antigen, GITR, GITR-D |
| Target Sequences: | NM_004195 NP_004186.1 Q9Y5U5 |
Publications (1)
1
Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states. Zhou Z, Song X, Berezov A, Zhang G, Li Y, Zhang H, Murali R, Li B, Greene MI. Proceedings of the National Academy of Sciences of the United States of America. 2008 105:5465-70.
[PubMed:18378892]
[PMC:PMC2291095]
Related Antibodies: LS-C41004.
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TNFRSF18 / GITR Mouse anti-Human Monoclonal (2H4) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TNFRSF18 / GITR Mouse anti-Human Monoclonal (621) Antibody
Human
Flo
Unconjugated
100 µg/$344
TNFRSF18 / GITR Mouse anti-Human Monoclonal (aa26-162) (OTI9G8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TNFRSF18 / GITR Mouse anti-Human Monoclonal (Biotin) (ANC7D6-1B7) Antibody
Human
ELISA, Flo
Biotin Conjugated
100 µg/$536
TNFRSF18 / GITR Mouse anti-Human Monoclonal (FITC) (ANC7D6-1B7) Antibody
Human
ELISA, Flo
FITC Conjugated
120 Tests/$536
TNFRSF18 / GITR Mouse anti-Human Monoclonal (Biotin) (ANC5E3) Antibody
Human
ELISA, Flo
Biotin Conjugated
100 µg/$536
TNFRSF18 / GITR Mouse anti-Human Monoclonal (FITC) (ANC5E3) Antibody
Human
ELISA, Flo
FITC Conjugated
120 Tests/$536
TNFRSF18 / GITR Mouse anti-Human Monoclonal (RPE) (ANC5E3) Antibody
Human
ELISA, Flo
RPE Conjugated
120 Tests/$561
TNFRSF18 / GITR Rat anti-Human Monoclonal (AIT 158D) Antibody
Human
ELISA, Flo
Unconjugated
50 µg/$337; 100 µg/$386
Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
TNFRSF18 / GITR Rat anti-Mouse Monoclonal (YGITR765.4.16) Antibody
Mouse
Flo, IHC, IHC-Fr
Unconjugated
250 µg/$465
TNFRSF18 / GITR Mouse anti-Human Monoclonal (4H2D6) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
TNFRSF18 / GITR Rat anti-Mouse Monoclonal (Biotin) (YGITR765.4.16) Antibody
Mouse
Flo, IHC
Biotin Conjugated
100 µg/$359
TNFRSF18 / GITR Mouse anti-Human Monoclonal (Azide-free) (ANC5E3) Antibody
Human
ELISA, Flo
Unconjugated, Azide-free
100 µg/$446
TNFRSF18 / GITR Rat anti-Mouse Monoclonal (DTA-1) Antibody
Mouse
Flo, IP
Unconjugated
100 µg/$386
TNFRSF18 / GITR Rat anti-Mouse Monoclonal (APC) (11n78) Antibody
Mouse
Flo
APC Conjugated
100 Tests/$839
TNFRSF18 / GITR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
TNFRSF18 / GITR Rabbit anti-Human Monoclonal (Preservative Free) (002) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
TNFRSF18 / GITR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
TNFRSF18 / GITR Mouse anti-Human Monoclonal (aa26-162) (UMAB203) Antibody
Human
IF, IHC, PMA
Unconjugated
100 µl/$493
TNFRSF18 / GITR Mouse anti-Human Monoclonal (aa26-162) (Carrier-free) (UMAB203) Antibody
Human
IF, IHC, PMA
Unconjugated, Carrier-free
100 µg/$539
TNFRSF18 / GITR Mouse anti-Human Monoclonal (6H8B9) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
Sandwich
96-Well Microplate
Human
13.7 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
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