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TNFRSF11A / RANK

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

TNFRSF11A / RANK is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Gene Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF11A, CD265, CD265 antigen, ODFR, LOH18CR1, OPTB7, OSTS, PDB2, RANK, Receptor activator of NF-KB, TRANCER, FEO, OFE
Target Sequences: NM_003839 NP_003830.1 Q9Y6Q6

Publications (2)

1
Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation. Yugo Morita, Motoo Saito, Javier Rangel-Moreno, Anthony M Franchini, John R Owen, John C Martinez, John L Daiss, Karen L de Mesy Bentley, Stephen L Kates, Edward M Schwarz, Gowrishankar Muthukrishnan. Bone research. 2022 August;10:56. [Full Text Article] [PubMed:36028492] [PMC:PMC9418173] Related Antibodies: LS-B2077.
2
Granulomatous Inflammation and Hypercalcemia in Patients With Severe Systemic Oxalosis. Peggy Perrin, Jérome Olagne, Arnaud Delbello, Stanislas Bataille, Laurent Mesnard, Claire Borni, Bruno Moulin, Sophie Caillard. Kidney international reports. 2022 February;7:343-349. [Full Text Article] [PubMed:35155875] [PMC:PMC8820998] Related Antibodies: LS-B11252.

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ELISA Kits (30)
Sandwich (26)
Sandwich CLIA (4)
TNFRSF11A / RANK (30)
Human (11)
Mouse (9)
Rat (5)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (5)
96-Well Microplate (6)
96-Well Strip Plate (17)
No (30)
Cell Culture Supernatants (9)
Cell Lysates (6)
Cell Supernatant (1)
Plasma (16)
Serum (24)
Tissue Homogenates (5)
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$699
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Microplate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$699
TNFRSF11A / RANK ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Mouse
625 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$699
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Microplate
Human
0.41 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
TNFRSF11A / RANK ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
63 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
Mouse
62.5 - 4000 pg/ml
Cell Culture Supernatants, Serum
1 Plate/$699
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
Rat
62.5 - 4000 pg/ml
Cell Culture Supernatants, Serum
1 Plate/$699
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$598
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$624
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$624
TNFRSF11A / RANK ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
TNFRSF11A / RANK ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
20 - 1250 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$562
TNFRSF11A / RANK ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
TNFRSF11A / RANK ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Rat
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$624
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).