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Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
Gene Name: | transmembrane protease, serine 15 |
Family/Subfamily: | Protease , Serine S1 |
Synonyms: | TMPRSS15, Enteropeptidase, Enterokinase, ENTK, PRSS7, Serine protease 7 |
Target Sequences: | NM_002772 NP_002763.2 P98073 |
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