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Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract.
Gene Name: | T-cell leukemia homeobox 2 |
Synonyms: | TLX2, Enx, Homeobox protein Hox-11L1, Neural crest homeobox protein, Homeo box 11-like 1, T-cell leukemia homeobox 2, NCX, HOX11L1, T-cell leukemia, homeobox 2 |
Target Sequences: | NM_016170 NP_057254.1 O43763 |
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