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TLR1

toll-like receptor 1

TLR1 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

Gene Name: toll-like receptor 1
Family/Subfamily: Toll-like Receptor , not assigned-Toll-like Receptor
Synonyms: TLR1, CD281 antigen, KIAA0012, Rsc786, Toll-like receptor 1, TIL. LPRS5, TIL, CD281
Target Sequences: NM_003263 NP_003254.2 Q15399

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Proteins (5)
Recombinant (5)
TLR1 (5)
No (5)
6His, N-terminus (1)
GST (1)
His-GST (1)
His-S (2)
Human (4)
Mouse (1)
E. coli (3)
Wheat Germ Extract (1)
Yeast (1)
Purified (2)
TLR1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
1 mg/$1,973; 100 µg/$570; 20 µg/$395
TLR1 Protein - Recombinant Toll Like Receptor 1 By SDS-PAGE
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E. coli
His-GST
42.6 kDa
10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796
TLR1 Protein - 12.5% SDS-PAGE of human TLR1 stained with Coomassie Blue
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Wheat Germ Extract
GST
116.7 kDa
10 µg/$479; 25 µg/$670
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E. coli
His-S
27.3 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
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E. coli
His-S
32.3 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).