TK2

thymidine kinase 2, mitochondrial

TK2 is a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

TK2 (6)

Publications

No (6)

Tag

10His, N-terminus + Myc, C-terminus (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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TK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100343

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31 kDa

Price:

100 µg/$494

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Human TK2 Protein (Recombinant 10His, N-terminus + Myc, C-terminus) (aa34-265) - LS-G56580

Source:

E. coli

Tag:

10His, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human TK2 Protein (Recombinant GST, N-terminus) (aa208-307) - LS-G60360

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79154

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31 kDa

Price:

20 µg/$150

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Human TK2 Protein (Recombinant His, N-Terminal) - LS-G144782

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

27.4 kDa

Price:

50 µg/$419

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Human TK2 Protein (Recombinant His) - LS-G1867

Source:

E. coli

Tag:

His

Price:

50 µg/$373; 250 µg/$769; 10 µg/$276; 20 µg/$329; 100 µg/$479; 500 µg/$1,243

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