TIGAR

chromosome 12 open reading frame 5

TIGAR is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.

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Products

ELISA Kits (4)

Type

Custom (1)

Sandwich (3)

Target

TIGAR (4)

Reactivity

Human (2)

Mouse (1)

Bovine (1)

Format

96-Well Strip Plate (4)

Publications

No (4)

Sample Type

Plasma (3)

Serum (3)

Tissue Homogenates (1)

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Human TIGAR (Sandwich ELISA) ELISA Kit - LS-F56088

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

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Bovine TIGAR (Custom ELISA) ELISA Kit - LS-F49397

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Mouse TIGAR (Sandwich ELISA) ELISA Kit - LS-F49764

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human TIGAR (Sandwich ELISA) ELISA Kit - LS-F49765

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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