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The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis.
Gene Name: | Thrombospondin, type I, domain containing 7A |
Synonyms: | THSD7A |
Target Sequences: | NM_015204 NP_056019.1 |
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